Irritation and corrosion tests:

• Skin irritation/corrosion / OECD 404 
• Eye irritation/corrosion / OECD 405 
• Eye irritation: Reconstructed Human Cornea-like Epithelium (RHCE) test method / OECD 492 
• In vitro skin irritation: reconstructed skin model / OECD 439 
• In vitro skin corrosion: reconstructed skin model  / OECD 431 
• In vitro skin corrosion: membrane barrier method / OECD 435 

Sensitisation tests:

• Skin sensitisation according to BUEHLER / OECD 406 
• Skin sensitisation according to the MAGNUSSON AND KLIGMAN method / OECD 406 
• Skin sensitization in mice: local lymph node stimulation test: LLNA-BRDU method / OECD 442B 
• In vitro KeratinoSens test** / OECD 442D 
• In vitro DPRA ** / OECD 442C 
• In vitro H-CLAT** / OECD 442E  

Acute toxicity tests:

• Acute dermal toxicity / OECD 402 
• Acute oral toxicity / OECD 423 
• Acute oral toxicity: up-and-down method / OECD 425 
• Acute oral toxicity: fixed-dose method / OECD 420 

Repeated-dose toxicity tests:

• 28-day oral toxicity** / OECD 407 
• 90-day oral toxicity** / OECD 408 

Inhalation toxicity tests:

• Inhalation** / OECD 436 

Skin absorption tests:

• Skin absorption** / OECD 427 
• Skin absorption ** / OECD 428 

Genotoxicity:

• Tests for reverse mutations in “Salmonella typhimurium his-” and “Escherichia coli” or Ames test (OECD 471) 

• In vitro study of chromosomal aberrations in mammalian cells (human lymphocytes, CHO) (OECD 473) 

• In vitro gene mutation tests in mammalian cells (L5178Y) (OECD 490) 

• In vitro micronucleus test in mammalian cells (CHO) (OECD 487) 

• Micronucleus test in rats (OECD 474)